Controversial idea to speed coronavirus vaccine gains ground - Bio-Defense Network
Apr 2020

Controversial idea to speed coronavirus vaccine gains ground

Peter Sullivan writes in The Hill about an idea that might seem outlandish at first is gaining some ground as a way to speed development of a coronavirus vaccine: intentionally infecting people with the virus as part of a trial.

The idea, known as a “challenge trial,” would deliberately infect a few hundred young, healthy volunteers, who were first given either the potential vaccine or a placebo. Those picked would be well informed about the risks.

That would allow the effectiveness of a vaccine to be determined faster than a traditional clinical trial, which would require that researchers wait for some of the participants to become infected in the course of their daily lives.  

Supporters say the challenge trial could save several months in the search for a vaccine, which is widely seen as critical for people to feel confident again with social gatherings. 

A group of 35 House lawmakers, led by Reps. Bill Foster (D-Ill.) and Donna Shalala (D-Fla.), a former secretary of Health and Human Services, wrote to the Food and Drug Administration this week lending their support to the idea. 

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